Leukoplakia is the most common potentially malignant disorder occuring in the oral cavity. It is of utmost significance to differentiate it from other benign

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30 Sep 2019 Leukoplakia is a condition that causes white patches or plaques to develop on the tongue and mucosa in the mouth. Mouth irritants and 

English; Français; Home ; Research projects. Breast cancer prevention and early detection; Cancer control; Cervical cancer prevention and early detection; Colorectal cancer prevention and early detection; Lung cancer early prevention and detection; Leukoplakia Differential Diagnosis The differential diagnosis of this disorder involves distinguishing it from other conditions that produce similar symptoms. Homogeneous leukoplakia: A predominantly white lesion of uniform, flat, thin appearance that may exhibit shallow cracks and has a smooth wrinkled or corrugated surface with a consistent texture throughout. • Nonhomogeneous leukoplakia: A predominantly white or white and red lesion that may be irregular, flat, nodular, or corrugated.

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• Nonhomogeneous leukoplakia: A predominantly white or white and red lesion that may be irregular, flat, nodular, or corrugated. Introduction: Leukoplakia (LKP) is defined as a white patch or plaque on the mucosa of oral cavity, vulva, vagina etc., which cannot be removed and cannot be clinically or microscopically explained by presence of a disease. LKP is included in the group of lesions with malignant potential. Microscopic characteristics: Basic microscopic characteristics of oral LKP include hyperkeratosis of ortho Differential diagnosis includes lichen planus, lupus, leukoedema, candidosis, white sponge naevus, frictional lesions, morsicatio lesions, contact lesions, and smoker’s palate. Histopathological study of leukoplakia allows the clinician: 1.- to exclude any other definable lesions; and 2.- to establish the degree of epithelial dysplasia, if present. CONCLUSIONS:Differential diagnosis of leukoplakia and LP in the oral mucosa based on digital texture analysis in intraoral macrophotography is possible. It can be used to develop smartphone applications and can be also a helpful tool for general dentists to define the clinical problem before a … Differential Diagnosis The following conditions should be considered before making a diagnosis of leukoplakia: Lichen Planus; Cinnamon Contact Stomatitis; Candidiasis; Hairy Leukoplakia; Lichenoid reactions; Chronic biting; Smokers Keratosis; Leukœdema; Chemical burn (such as Aspirin) Uræmic Stomatitis; Skin graft and; Discoid Lupus Erythematosus.

Conclusions: The differential diagnosis of oral lichen planus - particularly its reticular form - and homogenous leukoplakia should be based on anamnesis, physical examination and histological

Ulcerated leukoplakia4. Speckled leukoplakia5. Verrucous leukoplakia6.

Differential diagnosis of homogenous leukoplakia

Microscopic differential diagnosis: The most important differential diagnostic criteria are listed for lesions with similar microscopic appearance. Conclusion: Nowdays LKP is diagnosed more frequently than before, probable due to a better patients' education and dentists' caution, but not due to real increase in incidence.

There are many other conditions that are similar in appearance and must be ruled out before a diagnosis of erythroplakia is made (see table).

Differential Diagnosis The first step in developing a differential diagnosis for a white patch (leukoplakia) on the oral mucosa is to determine whether the lesion can be removed with a gauze square or a tongue blade. If the lesion can be removed, it may represent a pseudomembrane, a fungus colony, or debris. Term leukoplakia / leukoplakic also used descriptively in clinical setting to denote any white lesion without a readily apparent diagnosis Such use may skew understanding of leukoplakia biology / behavior due to preponderance of frictional / reactive keratoses in oral cavity, which are not always recognizable clinically but have no malignant potential ( Head Neck Pathol 2019;13:423 ) DIFFERENTIAL DIAGNOSIS OF HOMOGENOUS LEUKOPLAKIA • Lichen Planus(Wickham’s striae, skin lesions, feather margins, > women) • Leukoedema (milky opalescense, extent, elimination on stretching) • Cheek-biting lesion (history & clinical examination, jagged tooth) • Smokeless tobacco lesion (h/o smokeless tobacco use, lesion in vestibule) • Hyperplastic/ Hypertrophic Candidiasis(clinical & h/p examination) Differential diagnosis includes lichen planus, lupus, leukoedema, candidosis, white sponge naevus, frictional lesions, morsicatio lesions, contact lesions, and smoker’s palate. Histopathological study of leukoplakia allows the clinician: 1.- to exclude any other definable lesions; and 2.- to establish the degree of epithelial dysplasia, if present.
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Removal of known risk factors (tobacco, alcohol, betel and trauma) is a mandatory step. Up to 45% of Figure 1: Homogeneous oral leukoplakia in the left lateral border and ventrum of the tongue.

Leukoplakia is different from other causes of white patches such as thrush or lichen planus because it can eventually develop into oral cancer. Within 15 years, about 3% to 17.5% of people with leukoplakia will develop squamous cell carcinoma, a Differential diagnosis of an oral red lesion.
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25 Jul 2016 The clinical differential diagnosis for PVL would include frictional keratosis, homogenous leukoplakia, squamous papilloma, verrucous 

This type is usually asymptomatic. 2019-08-05 · Oral hairy leukoplakia (OHL) is a disease of the mucosa first described in 1984. This pathology is associated with Epstein-Barr virus (EBV) and occurs mostly in people with HIV, both immunocompromised and immunocompetent, albeit it can affect patients who are HIV negative. Homogeneous leukoplakia: A predominantly white lesion of uniform, flat, thin appearance that may exhibit shallow cracks and has a smooth wrinkled or corrugated surface with a consistent texture throughout. • Nonhomogeneous leukoplakia: A predominantly white or white and red lesion that may be irregular, flat, nodular, or corrugated.